Bigfloat routine for Incomplete Beta



You could try doing some or all of the calculation in rational numbers, and
converting
to bigfloat at the end.  

This might be slower.

Another way, non-portable, is to use the MPFR library for the elementary
operations.  
The library itself is
fairly portable, but the lisp-to-MPFR interface varies from one common lisp
to another.

MPFR may already have a gamma function that can be used directly from the
library..

http://cvs.sourceforge.jp/cgi-bin/viewcvs.cgi/pf3gnuchains/mpfr/gamma.c